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NAD+ (Nicotinamide Adenine Dinucleotide)
NAD+ is a critical coenzyme present in all living cells, widely studied for its role in cellular metabolism and energy production. It functions as a key redox mediator, alternating between NAD+ and NADH forms to facilitate electron transfer in fundamental biological reactions.
In research settings, NAD+ has been examined for its involvement in over 500 enzymatic processes, including those related to mitochondrial function, oxidative stress, and cellular homeostasis. It also plays a regulatory role in pathways involving sirtuins and PARPs—enzymes studied for their impact on DNA repair, gene expression, and genomic stability.
Due to its wide-ranging activity in energy metabolism and cell regulation, NAD+ remains a major focus in studies related to aging, cellular resilience, and overall metabolic health.
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