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Tesamorelin is a synthetic analog of growth hormone releasing hormone (GHRH), studied for its ability to stimulate endogenous GH production by binding to GHRH receptors. It has been FDA-approved for the reduction of visceral adipose tissue and is widely researched for its role in IGF-1 regulation, lipid metabolism, and cognitive pathways in preclinical models.
Ipamorelin is a highly selective GH secretagogue and ghrelin receptor agonist. It has been studied for its unique ability to stimulate GH release without significantly affecting other hormone levels such as cortisol or prolactin. Ipamorelin remains a widely researched compound in models examining tissue regeneration, metabolic health, and GH modulation.
Together, Tesamorelin and Ipamorelin are often explored in combination for their complementary mechanisms in stimulating the growth hormone axis, with particular interest in models involving metabolic function, recovery, and age-related hormone dynamics.
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